The low temperature sterilization method is a method of killing pathogenic microorganisms using a chemical sterilizing agent. The temperature required for sterilization of chemicals is low, and is often referred to as a low temperature sterilization method or a chemical sterilization method. The chemical disinfectant used for low-temperature sterilization can kill all microorganisms and achieve the level of sterilization assurance. Such chemical agents with sterilization effects include formaldehyde, glutaraldehyde, ethylene oxide, peracetic acid and the like. Chemical sterilization is used for sterilization of instruments that cannot withstand high temperature, damp heat materials.
Commonly used low temperature sterilization methods include hydrogen peroxide plasma low temperature sterilization, ethylene oxide sterilization, and low temperature formaldehyde steam sterilization.
1. Hydrogen peroxide plasma low temperature sterilization
The article is sterilized by dispersing the hydrogen peroxide liquid into a gaseous state, and the second stage sterilization is performed by the generated plasma. The plasma process also accelerates and completely decomposes the residual hydrogen peroxide gas on the instrument and packaging materials. The plasma sterilization method is characterized by rapid action, reliable sterilization, low temperature action, and clean and non-toxic residue. Applicable to endoscopes, heat-resistant equipment, all kinds of metal equipment, glass and other items; can absorb moisture and gas.
2. Ethylene oxide sterilization
Ethylene oxide is a colorless gas with a similar odor to ether and no taste at low concentrations. It has strong gas breakthrough and penetrates cellophane, polyethylene or polyvinyl chloride film, etc. It produces non-specific alkylation of microbial proteins, DNA and RNA, and it is killed by losing the basic reactive base of metabolism. It has strong bactericidal power, wide spectrum of killing, reliable sterilization effect and less damage to sterilized articles.